癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-GTP Cyclohydrolase 1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P30793 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB13125 |
| Calculated MW | 27903 Da |
| Gene Name | GCH1 |
| Aliases | GCH1; GTP Cyclohydrolase 1; GTP Cyclohydrolase I; GTPCH1; DYT5a; DYT5; GCH; Dystonia 14; EC 3.5.4.16; GTP-CH-I; DYT14; Guanosine 5'-Triphosphate Cyclohydrolase I; Dopa-Responsive Dystonia; GTP-CH-1; HPABH4B |
| Immunogen | Recombinant protein of human GCH1 |
| Gene ID | 2643 |
|---|---|
| Other Names | GTP cyclohydrolase 1, 3.5.4.16, GTP cyclohydrolase I, GTP-CH-I, GCH1, DYT5, GCH |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GCH1 |
|---|---|
| Synonyms | DYT5, GCH |
| Function | Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown. |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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