癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-PDE1B Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q01064 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b |
| Clone Names | 24GB13240 |
| Calculated MW | 61380 Da |
| Gene Name | PDE1B |
| Aliases | PDE1B; Phosphodiesterase 1B; PDES1B; Dual Specificity Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B; Phosphodiesterase 1B, Calmodulin-Dependent; 63 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1B; Presumed 63kDa Form Of The Type 1 Cyclic Nucleotide Phosphodiesterase Family Known As PDE1B; Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B; Calcium/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase; Epididymis Secretory Sperm Binding Protein Li 79p; Calmodulin-Stimulated Phosphodiesterase PDE1B1; HEL-S-79p; EC 3.1.4; PDE1B1 |
| Immunogen | Recombinant protein of human PDE1B |
| Gene ID | 5153 |
|---|---|
| Other Names | Dual specificity calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 3.1.4.17, 63 kDa Cam-PDE, PDE1B (HGNC:8775), PDES1B |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PDE1B (HGNC:8775) |
|---|---|
| Synonyms | PDES1B |
| Function | Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15260978, PubMed:8855339, PubMed:9419816). Has a preference for cGMP as a substrate (PubMed:9419816). |
| Cellular Location | Cytoplasm, cytosol. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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