癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-PDLIM7 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9NR12 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB13710 |
| Calculated MW | 49845 Da |
| Gene Name | PDLIM7 |
| Aliases | PDLIM7; PDZ And LIM Domain 7; ENIGMA; PDZ And LIM Domain 7 (Enigma); PDZ And LIM Domain Protein 7; Protein Enigma; LMP; Lim Mineralization Protein 3; LIM Mineralization Protein; LIM Domain Protein; 1110003B01Rik; LMP1; LMP3 |
| Immunogen | Recombinant protein of human PDLIM7 |
| Gene ID | 9260 |
|---|---|
| Other Names | PDZ and LIM domain protein 7, LIM mineralization protein, LMP, Protein enigma, PDLIM7, ENIGMA |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PDLIM7 |
|---|---|
| Synonyms | ENIGMA |
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). |
| Tissue Location | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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