癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-ACAT1 Rabbit Polyclonal Antibody
Rabbit polyclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P24752 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45200 Da |
| Gene Name | ACAT1 |
| Aliases | ACAT1; Acetyl-CoA Acetyltransferase 1; THIL; ACAT; Acetyl-CoA Acetyltransferase, Mitochondrial; Acetyl-Coenzyme A Acetyltransferase 1; Acetoacetyl Coenzyme A Thiolase; Acetoacetyl-CoA Thiolase; EC 2.3.1.9; MAT; T2; Mitochondrial Acetoacetyl-CoA Thiolase; Testicular Tissue Protein Li 198; EC 2.3.1 |
| Immunogen | A synthesized peptide derived from human ACAT1 |
| Gene ID | 38 |
|---|---|
| Other Names | Acetyl-CoA acetyltransferase, mitochondrial, 2.3.1.9 {ECO:0000255|PROSITE-ProRule:PRU10020, ECO:0000269|PubMed:1715688, ECO:0000269|PubMed:17371050, ECO:0000269|PubMed:7728148, ECO:0000269|PubMed:9744475}, Acetoacetyl-CoA thiolase, T2, ACAT1, ACAT, MAT |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ACAT1 |
|---|---|
| Synonyms | ACAT, MAT |
| Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (PubMed:1715688, PubMed:7728148, PubMed:9744475). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (PubMed:1715688, PubMed:7728148, PubMed:9744475). The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA (PubMed:17371050). Thereby, it plays a major role in ketone body metabolism (PubMed:1715688, PubMed:17371050, PubMed:7728148, PubMed:9744475). |
| Cellular Location | Mitochondrion. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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