癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-PDLIM1 Rabbit Polyclonal Antibody
Rabbit polyclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O00151 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36072 Da |
| Gene Name | PDLIM1 |
| Aliases | PDLIM1; PDZ And LIM Domain 1; CLP36; CLP-36; HCLIM1; Elfin; CLIM1; Carboxyl Terminal LIM Domain Protein 1; PDZ And LIM Domain Protein 1; LIM Domain Protein CLP-36; Epididymis Secretory Protein Li 112; C-Terminal LIM Domain Protein 1; PDZ And LIM Domain 1 (Elfin); HEL-S-112 |
| Immunogen | A synthesized peptide derived from human PDLIM1 |
| Gene ID | 9124 |
|---|---|
| Other Names | PDZ and LIM domain protein 1, C-terminal LIM domain protein 1, Elfin, LIM domain protein CLP-36, PDLIM1, CLIM1, CLP36 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PDLIM1 |
|---|---|
| Synonyms | CLIM1, CLP36 |
| Function | Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (PubMed:10861853). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line Note=Associates with actin stress fibers |
| Tissue Location | Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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