癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-SH3GL1 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q99961 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB13930 |
| Calculated MW | 41490 Da |
| Gene Name | SH3GL1 |
| Aliases | SH3GL1; SH3 Domain Containing GRB2 Like 1, Endophilin A2; SH3D2B; CNSA1; EEN; SH3P8; Extra Eleven-Nineteen Leukemia Fusion Gene Protein; SH3 Domain-Containing GRB2-Like Protein 1; SH3-Containing Grb-2-Like 1 Protein; Extra 11-19 Leukemia Fusion; EEN Fusion Partner Of MLL; SH3-Domain GRB2-Like 1; SH3 Domain Protein 2B; Endophilin-A2; Endophilin-2; MGC111371; SH3 Domain Containing GRB2 Like 1; SH3-Containing Protein EEN; SH3 Domain GRB2-Like 1; Fusion Partner Of MLL; Endophilin A2 |
| Immunogen | Recombinant protein of human SH3GL1 |
| Gene ID | 6455 |
|---|---|
| Other Names | Endophilin-A2, EEN fusion partner of MLL, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, EEN, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3GL1, CNSA1, SH3D2B |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SH3GL1 |
|---|---|
| Synonyms | CNSA1, SH3D2B |
| Function | Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles (By similarity). May recruit other proteins to membranes with high curvature (By similarity). |
| Cellular Location | Cytoplasm. Early endosome membrane; Peripheral membrane protein. Cell projection, podosome. Note=Associated with postsynaptic endosomes in hippocampal neurons. |
| Tissue Location | Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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