癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-RBBP7 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q16576 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB13975 |
| Calculated MW | 47820 Da |
| Gene Name | RBBP7 |
| Aliases | RBBP7; RB Binding Protein 7, Chromatin Remodeling Factor; Histone Acetyltransferase Type B Subunit 2; Retinoblastoma-Binding Protein P46; Retinoblastoma-Binding Protein 7; RbAp46; G1/S Transition Control Protein-Binding Protein RbAp46; Nucleosome-Remodeling Factor Subunit RBAP46; Retinoblastoma-Binding Protein RbAp46; Histone-Binding Protein RBBP7; RBBP-7; Retinoblastoma Binding Protein 7; RB Binding Protein 7; RBAP46 |
| Immunogen | Recombinant protein of human RBBP7 |
| Gene ID | 5931 |
|---|---|
| Other Names | Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RBBP7 |
|---|---|
| Synonyms | RBAP46 |
| Function | Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
| Cellular Location | Nucleus |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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