癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-NAGK Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q9UJ70 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB14215 |
| Calculated MW | 37376 Da |
| Gene Name | NAGK |
| Aliases | NAGK; N-Acetylglucosamine Kinase; GNK; N-Acetyl-D-Glucosamine Kinase; N-Acetyl-D-Mannosamine Kinase; Muramyl Dipeptide Kinase; GlcNAc Kinase; EC 2.7.1.59; Epididymis Secretory Sperm Binding Protein; EC 2.7.1.60; EC 2.7.1.-; HSA242910 |
| Immunogen | Recombinant protein of human NAGK |
| Gene ID | 55577 |
|---|---|
| Other Names | N-acetyl-D-glucosamine kinase, N-acetylglucosamine kinase, 2.7.1.59, GlcNAc kinase, Muramyl dipeptide kinase, 2.7.1.-, N-acetyl-D-mannosamine kinase, 2.7.1.60, NAGK {ECO:0000303|PubMed:36002575, ECO:0000312|HGNC:HGNC:17174} |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NAGK {ECO:0000303|PubMed:36002575, ECO:0000312|HGNC:HGNC:17174} |
|---|---|
| Function | Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate (PubMed:22692205). Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (PubMed:22692205). Also has N-acetylmannosamine (ManNAc) kinase activity (By similarity). Also involved in innate immunity by promoting detection of bacterial peptidoglycan by NOD2: acts by catalyzing phosphorylation of muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, to generate 6-O-phospho-muramyl dipeptide, which acts as a direct ligand for NOD2 (PubMed:36002575). |
| Tissue Location | Ubiquitous.. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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