癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-ASRGL1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q7L266 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB14255 |
| Calculated MW | 32055 Da |
| Gene Name | ASRGL1 |
| Aliases | ASRGL1; Asparaginase And Isoaspartyl Peptidase 1; ALP; ALP1; Isoaspartyl Peptidase/L-Asparaginase; Asparaginase-Like 1 Protein; L-Asparagine Amidohydrolase; Asparaginase-Like Protein 1; Beta-Aspartyl-Peptidase; Isoaspartyl Dipeptidase; Asparaginase Like 1; EC 3.5.1.1; FLJ22316; CRASH; Testis Secretory Sperm-Binding Protein Li 242mP; L-Asparaginase; EC 3.4.19.5 |
| Immunogen | Recombinant protein of human ASRGL1 |
| Gene ID | 80150 |
|---|---|
| Other Names | Isoaspartyl peptidase/L-asparaginase, 3.4.19.5, 3.5.1.1, Asparaginase-like protein 1, Beta-aspartyl-peptidase, Isoaspartyl dipeptidase, L-asparagine amidohydrolase, Isoaspartyl peptidase/L-asparaginase alpha chain, Isoaspartyl peptidase/L-asparaginase beta chain, ASRGL1, ALP, CRASH |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ASRGL1 |
|---|---|
| Synonyms | ALP, CRASH |
| Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp- L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. |
| Cellular Location | Cytoplasm. Note=Midpiece of sperm tail |
| Tissue Location | Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over- expressed in uterine, mammary, prostatic and ovarian carcinoma |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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