癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Cyclin T1 Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | O60563 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB150 |
| Calculated MW | 80685 Da |
| Gene Name | CCNT1 |
| Aliases | CCNT1; Cyclin T1; CYCT1; CCNT; Human Immunodeficiency Virus Type 1 (HIV-1) Expression (Elevated); Cyclin-T1; HIVE1; CDK9-Associated C-Type Protein; Cyclin C-Related Protein; MLLT10/CCNT1 Fusion; Cyclin-T; CycT1 |
| Immunogen | Recombinant protein of human Cyclin T1 |
| Gene ID | 904 |
|---|---|
| Other Names | Cyclin-T1, CycT1, Cyclin-T, CCNT1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CCNT1 |
|---|---|
| Function | Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II) (PubMed:16109376, PubMed:16109377, PubMed:30134174, PubMed:35393539). Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II (PubMed:29849146, PubMed:35393539). |
| Cellular Location | Nucleus |
| Tissue Location | Ubiquitously expressed. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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