癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-LPCAT1 Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q8NF37 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB180 |
| Calculated MW | 59151 Da |
| Gene Name | LPCAT1 |
| Aliases | LPCAT1; Lysophosphatidylcholine Acyltransferase 1; AGPAT10; AGPAT9; LPLAT8; AYTL2; Acetyl-CoA:Lyso-Platelet-Activating Factor Acetyltransferase; 1-Alkenylglycerophosphocholine O-Acyltransferase; 1-Alkylglycerophosphocholine O-Acetyltransferase; 1-Acylglycerophosphocholine O-Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Phosphonoformate Immuno-Associated Protein 3; Acetyl-CoA:Lyso-PAF Acetyltransferase; Lysophospholipid Acyltransferase 8; Lyso-PAF Acetyltransferase; LysoPC Acyltransferase 1; Acyltransferase-Like; LPC Acyltransferase 1; LysoPAFAT; FLJ12443; LPCAT-1; PFAAP3; Acyltransferase Like 2; EC 2.3.1.23; EC 2.3.1.51; EC 2.3.1.25; EC 2.3.1.67; Lpcat |
| Immunogen | Recombinant protein of human LPCAT1 |
| Gene ID | 79888 |
|---|---|
| Other Names | Lysophosphatidylcholine acyltransferase 1, LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1, 2.3.1.23, 1-acylglycerol-3-phosphate O-acyltransferase, 2.3.1.51, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT, Acyltransferase-like 2, Phosphonoformate immuno-associated protein 3, LPCAT1, AYTL2, PFAAP3 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LPCAT1 |
|---|---|
| Synonyms | AYTL2, PFAAP3 |
| Function | Exhibits acyltransferase activity (PubMed:18156367, PubMed:21498505). Exhibits acetyltransferase activity (By similarity). Activity is calcium-independent (By similarity). Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3- phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero- 3-phosphocholine or PC) (PubMed:18156367, PubMed:21498505). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity). Involved in platelet- activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (By similarity). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (By similarity). Involved in the regulation of lipid droplet number and size (PubMed:25491198). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q3TFD2}; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Lipid droplet. Note=May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm. |
| Tissue Location | Erythrocytes.. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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