癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-RAP1B Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | P61224 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB210 |
| Calculated MW | 20825 Da |
| Gene Name | RAP1B |
| Aliases | RAP1B; RAP1B, Member Of RAS Oncogene Family; K-REV; RAL1B; GTP-Binding Protein Smg P21B; Ras-Related Protein Rap-1b; DKFZp586H0723; Ras Family Small GTP Binding Protein RAP1B; RAS-Related Protein RAP1B; Small GTP Binding Protein; EC 3.6.5.2; THC11 |
| Immunogen | A synthesized peptide derived from human RAP1A/B |
| Gene ID | 5908 |
|---|---|
| Other Names | Ras-related protein Rap-1b, 3.6.5.2, GTP-binding protein smg p21B, RAP1B |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RAP1B |
|---|---|
| Function | GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. |
| Cellular Location | Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol (PubMed:3141412). Presence of KRIT1 and CDH5 is required for its localization to the cell junction (PubMed:20332120) |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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