癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-NDUFS1 Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | P28331 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB240 |
| Calculated MW | 79468 Da |
| Gene Name | NDUFS1 |
| Aliases | NDUFS1; NADH:Ubiquinone Oxidoreductase Core Subunit S1; NADH-Ubiquinone Oxidoreductase 75 KDa Subunit, Mitochondrial; CI-75k; NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase); Complex I 75kDa Subunit 2 3NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1 (75kD) (NADH-Coenzyme Q Reductase); Mitochondrial NADH-Ubiquinone Oxidoreductase 75 KDa Subunit; Complex I, Mitochondrial Respiratory Chain, 75-KD Subunit; Complex I-75kD; EC 7.1.1.2; CI-75Kd; PRO1304; CI-75kD; MC1DN5 |
| Immunogen | A synthesized peptide derived from human Ndufs1 |
| Gene ID | 4719 |
|---|---|
| Other Names | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, 7.1.1.2, Complex I-75kD, CI-75kD, NDUFS1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NDUFS1 |
|---|---|
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P15690}; Matrix side {ECO:0000250|UniProtKB:P15690} |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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