癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-ZC3HC1 Mouse Oligoclonal Antibody
Mouse oligoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q86WB0 |
| Reactivity | Human, Mouse |
| Clonality | Oligoclonal |
| Isotype | Mouse IgG |
| Calculated MW | 55262 Da |
| Gene Name | ZC3HC1 |
| Aliases | ZC3HC1; Zinc Finger C3HC-Type Containing 1; NIPA; Nuclear-Interacting Partner Of ALK; Zinc Finger C3HC-Type Protein 1; Nuclear Interacting Partner Of Anaplastic Lymphoma Kinase (ALK); Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase; Hematopoietic Stem/Progenitor Cell Protein 216; Nuclear Interaction Partner Of ALK; HSPC216; HNIPA |
| Immunogen | Recombinant protein of human ZC3HC1 |
| Gene ID | 51530 |
|---|---|
| Other Names | Zinc finger C3HC-type protein 1, Nuclear-interacting partner of ALK, hNIPA, Nuclear-interacting partner of anaplastic lymphoma kinase, ZC3HC1 (HGNC:29913) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZC3HC1 (HGNC:29913) |
|---|---|
| Function | Required for proper positioning of a substantial amount of TPR at the nuclear basket (NB) through interaction with TPR. |
| Cellular Location | Nucleus. Nucleus envelope. Note=Resident of the nuclear basket (NB) (PubMed:34440706). Occurs at the nuclear envelopes (NE) of all TPR-containing cell types, including proliferating and non- dividing, terminally differentiated cells of different morphogenetic origin (PubMed:34440706). |
| Tissue Location | Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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