癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-UBE2F Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q969M7 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB940 |
| Calculated MW | 21077 Da |
| Gene Name | UBE2F |
| Aliases | UBE2F; Ubiquitin Conjugating Enzyme E2 F (Putative); NCE2; Ubiquitin-Conjugating Enzyme E2F (Putative); RING-Type E3 NEDD8 Transferase UBE2F; NEDD8-Conjugating Enzyme UBE2F; NEDD8 Carrier Protein UBE2F; NEDD8 Protein Ligase UBE2F; NEDD8-Conjugating Enzyme 2; Ubiquitin-Conjugating Enzyme E2 F; NEDD8 Conjugating Enzyme; EC 2.3.2.34; EC 6.3.2 |
| Immunogen | Recombinant protein of human UBE2F |
| Gene ID | 140739 |
|---|---|
| Other Names | NEDD8-conjugating enzyme UBE2F, 2.3.2.34, NEDD8 carrier protein UBE2F, NEDD8 protein ligase UBE2F, NEDD8-conjugating enzyme 2, RING-type E3 NEDD8 transferase UBE2F, Ubiquitin-conjugating enzyme E2 F, UBE2F, NCE2 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | UBE2F |
|---|---|
| Synonyms | NCE2 |
| Function | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins (PubMed:19250909, PubMed:23201271). Together with the E3 ubiquitin ligase RNF7/RBX2, specifically neddylates cullin-5 (CUL5) (PubMed:19250909, PubMed:23201271, PubMed:23300442). Does not neddylate CUL1, CUL2, CUL3, CUL4A or CUL4B (PubMed:19250909, PubMed:23201271). Mediates neddylation of the CUL9-RBX1 complex (PubMed:38605244). |
| Tissue Location | Widely expressed (at protein level). |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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