癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-FAM98B Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q52LJ0 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4315 |
| Calculated MW | 45547 Da |
| Gene Name | FAM98B |
| Aliases | FAM98B; Family With Sequence Similarity 98 Member B; Protein FAM98B; FLJ38426; Family With Sequence Similarity 98, Member B |
| Immunogen | Recombinant protein of human FAM98B |
| Gene ID | 283742 |
|---|---|
| Other Names | Protein FAM98B, FAM98B |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | FAM98B (HGNC:26773) |
|---|---|
| Function | Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity and may function toward other RNAs (PubMed:21311021, PubMed:24870230). Could regulate the expression of PRMT1, a protein arginine N-methyltransferase (PubMed:28040436). |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (at protein level) (PubMed:28040436). Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (PubMed:28040436) |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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