癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-FNTA Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P49354 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4325 |
| Calculated MW | 44409 Da |
| Gene Name | FNTA |
| Aliases | FNTA; Farnesyltransferase, CAAX Box, Subunit Alpha; Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha; PGGT1A; PTAR2; FPTA; Protein Prenyltransferase Alpha Subunit Repeat Containing 2; Ras Proteins Prenyltransferase Subunit Alpha; Farnesyltransferase, CAAX Box, Alpha; GGTase-I-Alpha; FTase-Alpha; Type I Protein Geranyl-Geranyltransferase Alpha Subunit; Type I Protein Geranyl-Geranyltransferase Subunit Alpha; Farnesyl-Protein Transferase Alpha-Subunit; CAAX Farnesyltransferase Subunit Alpha; EC 2.5.1.58; EC 2.5.1.59 |
| Immunogen | A synthesized peptide derived from human FNTA |
| Gene ID | 2339 |
|---|---|
| Other Names | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, 2.5.1.58, 2.5.1.59, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | FNTA |
|---|---|
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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