癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-POLDIP2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9Y2S7 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4415 |
| Calculated MW | 42033 Da |
| Gene Name | POLDIP2 |
| Aliases | POLDIP2; DNA Polymerase Delta Interacting Protein 2; PDIP38; Polymerase (DNA-Directed), Delta Interacting Protein 2; 38 KDa DNA Polymerase Delta Interaction Protein; Polymerase Delta-Interacting Protein 2; DKFZP586F1524; POLD4; P38; Polymerase (DNA) Delta Interacting Protein 2; Polymerase Delta Interacting Protein 38 |
| Immunogen | A synthesized peptide derived from human POLDIP2 |
| Gene ID | 26073 |
|---|---|
| Other Names | Polymerase delta-interacting protein 2, 38 kDa DNA polymerase delta interaction protein, p38, POLDIP2 {ECO:0000303|PubMed:26984527, ECO:0000312|HGNC:HGNC:23781} |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | POLDIP2 {ECO:0000303|PubMed:26984527, ECO:0000312|HGNC:HGNC:23781} |
|---|---|
| Function | Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527). |
| Cellular Location | Mitochondrion matrix. Nucleus Note=Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
