癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-SRP72 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O76094 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4490 |
| Calculated MW | 74606 Da |
| Gene Name | SRP72 |
| Aliases | SRP72; Signal Recognition Particle 72; Signal Recognition Particle 72 KDa Protein; Signal Recognition Particle Subunit SRP72; Signal Recognition Particle 72kDa; Signal Recognition Particle 72kD; Epididymis Luminal Protein 103; HEL103; BMFS1; BMFF |
| Immunogen | A synthesized peptide derived from human SRP72 |
| Gene ID | 6731 |
|---|---|
| Other Names | Signal recognition particle subunit SRP72, SRP72, Signal recognition particle 72 kDa protein, SRP72 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SRP72 |
|---|---|
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:34020957). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (PubMed:34020957). The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (PubMed:34020957). Binds the signal recognition particle RNA (7SL RNA) in presence of SRP68 (PubMed:21073748, PubMed:27899666). Can bind 7SL RNA with low affinity (PubMed:21073748, PubMed:27899666). The SRP complex possibly participates in the elongation arrest function (By similarity). |
| Cellular Location | Cytoplasm. Endoplasmic reticulum |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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