KD-Validated Anti-NFKBIE Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | O00221 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4800 |
| Calculated MW | 52864 Da |
| Gene Name | NFKBIE |
| Aliases | NFKBIE; NFKB Inhibitor Epsilon; IKBE; NF-Kappa-B Inhibitor Epsilon; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Epsilon; I-Kappa-B-Epsilon; IkappaBepsilon; NF-Kappa-BIE; IkB-Epsilon; IkB-E |
| Immunogen | A synthesized peptide derived from human NFKBIE |
| Gene ID | 4794 |
|---|---|
| Other Names | NF-kappa-B inhibitor epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon, NFKBIE, IKBE |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | NFKBIE |
|---|---|
| Synonyms | IKBE |
| Function | Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity (PubMed:9315679). Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50- c-Rel) complexes (PubMed:9135156, PubMed:9315679). Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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