癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KO Validated Anti-Integrin Subunit Alpha 2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | P17301 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB545 |
| Calculated MW | 129296 Da |
| Gene Name | ITGA2 |
| Aliases | ITGA2; Integrin Subunit Alpha 2; GPIa; VLAA2; HPA-5; CD49B; Integrin, Alpha 2 (CD49B, Alpha 2 Subunit Of VLA-2 Receptor); Very Late Activation Receptor Subunit Alpha-2; Alpha 2 Subunit Of VLA-2 Receptor; CD49 Antigen-Like Family Member B; Platelet Membrane Glycoprotein Ia; Human Platelet Alloantigen 5 2 3; Alpha 2 Integrin; Integrin Alpha-2; Glycoprotein Ia; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; Very Late Activation Receptor Alpha-2 Subunit; Human Platelet Alloantigen System 5; Platelet Glycoprotein GPIa; Platelet Antigen Br; VLA-2 Subunit Alpha; CD49b Antigen; VLA-2; BR |
| Immunogen | A synthesized peptide derived from human Integrin alpha 2 |
| Gene ID | 3673 |
|---|---|
| Other Names | Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, CD49B |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ITGA2 |
|---|---|
| Synonyms | CD49B |
| Function | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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