癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KO-Validated Anti-CD55 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P08174 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB435 |
| Calculated MW | 41400 Da |
| Gene Name | CD55 |
| Aliases | CD55; CD55 Molecule (Cromer Blood Group); CR; CROM; DAF; TC; CD55 Molecule, Decay AcceleRating Factor For Complement (Cromer Blood Group); Complement Decay-AcceleRating Factor; CD55 Antigen; Decay AcceleRating Factor For Complement (CD55, Cromer Blood Group System); Cromer Blood Group Antigen; Rh Blood Group D Antigen; CHAPLE |
| Immunogen | A synthesized peptide derived from human CD55 |
| Gene ID | 1604 |
|---|---|
| Other Names | Complement decay-accelerating factor, CD55, CD55, CR, DAF |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CD55 |
|---|---|
| Synonyms | CR, DAF |
| Function | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829). |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted [Isoform 5]: Secreted [Isoform 7]: Cell membrane; Lipid-anchor, GPI-anchor |
| Tissue Location | Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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