癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KO-Validated Anti-HADH Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q16836 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b |
| Clone Names | 25GB675 |
| Calculated MW | 34294 Da |
| Gene Name | HADH |
| Aliases | HADH; Hydroxyacyl-CoA Dehydrogenase; SCHAD; HADHSC; HADH1; Medium And Short-Chain L-3-Hydroxyacyl-Coenzyme A Dehydrogenase; L-3-Hydroxyacyl-Coenzyme A Dehydrogenase, Short Chain; Hydroxyacyl-Coenzyme A Dehydrogenase, Mitochondrial; Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase; EC 1.1.1.35; HCDH; HAD; Testis Secretory Sperm-Binding Protein Li 203a; Hydroxyacyl-Coenzyme A Dehydrogenase; EC 1.1.1; MSCHAD; HHF4; HAD1 |
| Immunogen | Recombinant protein of human HADH |
| Gene ID | 3033 |
|---|---|
| Other Names | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial, HCDH, 1.1.1.35, Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase, Short-chain 3-hydroxyacyl-CoA dehydrogenase, HADH |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | HADH |
|---|---|
| Function | Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10) (PubMed:10231530, PubMed:11489939, PubMed:16725361). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion (By similarity). Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity). |
| Cellular Location | Mitochondrion matrix |
| Tissue Location | Expressed in liver, kidney, pancreas, heart and skeletal muscle. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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