癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KO-Validated Anti-Ribosomal Protein SA Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P08865 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB2950 |
| Calculated MW | 32854 Da |
| Gene Name | RPSA |
| Aliases | RPSA; Ribosomal Protein SA; 37LRP; LAMR1; LRP; P40; US2; SA; Laminin Receptor 1 (67kD, Ribosomal Protein SA); Multidrug Resistance-Associated Protein MGr1-Ag; Colon Carcinoma Laminin-Binding Protein; Laminin-Binding Protein Precursor P40; Small Ribosomal Subunit Protein US2; 37/67 KDa Laminin Receptor; 40S Ribosomal Protein SA; 67 KDa Laminin Receptor; NEM/1CHD4; LBP/P40; LRP/LR; LAMBR; 67LR; LamR; 37 KDa Laminin Receptor Precursor; 37 KDa Laminin Receptor; Laminin Receptor 1; ICAS; LBP |
| Immunogen | A synthesized peptide derived from human 67kDa Laminin Receptor |
| Gene ID | 3921 |
|---|---|
| Other Names | Small ribosomal subunit protein uS2 {ECO:0000255|HAMAP-Rule:MF_03016, ECO:0000303|PubMed:24524803}, 37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}, 37LRP {ECO:0000255|HAMAP-Rule:MF_03016}, 37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}, 40S ribosomal protein SA, 67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}, 67LR {ECO:0000255|HAMAP-Rule:MF_03016}, Colon carcinoma laminin-binding protein, Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}, LamR {ECO:0000255|HAMAP-Rule:MF_03016}, Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}, LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, RPSA {ECO:0000255|HAMAP-Rule:MF_03016}, LAMBR, LAMR1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RPSA {ECO:0000255|HAMAP-Rule:MF_03016} |
|---|---|
| Synonyms | LAMBR, LAMR1 |
| Function | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. |
| Cellular Location | Cell membrane. Cytoplasm. Nucleus {ECO:0000255|HAMAP-Rule:MF_03016}. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity) Colocalizes with PPP1R16B in the cell membrane. {ECO:0000255|HAMAP- Rule:MF_03016} |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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