癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IPO-38 (Proliferation Marker) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone IPO-38 ]
- 产品详情
- 实验流程
- 背景知识
Application 
| IF, FC, IHC-P |
|---|---|
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgM, kappa |
| Clone Names | IPO-38 |
| Calculated MW | 14 KDa |
| Application Note | IF~~1:50~200 FC~~1:10~50 IHC-P~~1:50~200 |
|---|---|
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | IPO-38 (Proliferation Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression.
REFERENCES
Sidorenko SP et al. Monoclonal antibodies of the IPO series in studying and diagnosing malignant lympho-proliferative diseases. Gematol Transfuziol 1990, 35(4):19-22. Mikhalap SV et al. Monoclonal antibody IPO-38 recognizes a novel nuclear antigen of proliferating cells. In Kishimoto T et al eds. Leukocyte Typing VI, p609-610, Garland Publishing, New York, 1997.Mathews MB et al. Identity of the proliferating cell nuclear antigen and cyclin. Nature 1984, 309:374-376
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