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细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ZBTB4 antibody - middle region
Rabbit Polyclonal Antibody
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- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q9P1Z0 |
| Other Accession | Q9P1Z0, NP_065950, NM_020899 |
| Reactivity | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse |
| Predicted | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 105114 Da |
| Gene ID | 57659 |
|---|---|
| Alias Symbol | KAISO-L1, KIAA1538, ZNF903 |
| Other Names | Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538 |
| Target/Specificity | ZBTB4 may be involved in transcriptional regulation. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-ZBTB4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | ZBTB4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZBTB4 |
|---|---|
| Synonyms | KIAA1538 |
| Function | Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self- renewal (By similarity). |
| Cellular Location | Nucleus. Chromosome. Note=Localizes to chromocenters |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This is a rabbit polyclonal antibody against ZBTB4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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