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SOX15 antibody - middle region

Rabbit Polyclonal Antibody

     
  • 1 - SOX15 antibody - middle region AI10084
    SOX15 antibody - middle region (AI10084) in Transfected 293T cells using Western Blot
    WB Suggested Anti-SOX15 Antibody Titration: 0.2-1 µg/ml
    ELISA Titer: 1:62500
    Positive Control: Transfected 293T
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O60248
Other Accession O60248, NP_008873, NM_006942
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Bovine
Predicted Human, Mouse, Dog, Guinea Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 25251 Da
Additional Information
Gene ID 6665
Alias Symbol SOX20, SOX26, SOX27
Other Names Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
Target/Specificity SOX15 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SOX15 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSOX15 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX15
Synonyms SOX12, SOX20, SOX26, SOX27
Function Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence (By similarity). Acts as a transcriptional activator and repressor (By similarity). Binds synergistically with POU5F1 (OCT3/4) to gene promoters (By similarity). Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation (By similarity). Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG (By similarity). Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity (By similarity). Regulates transcription of HRC via binding to it proximal enhancer region (By similarity). Involved in skeletal muscle regeneration (By similarity). Also plays a role in the development of myogenic precursor cells (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Tissue Location Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This is a rabbit polyclonal antibody against SOX15. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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