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>   首页   >   产品   >   一抗   >   精选抗体   >   斑马鱼抗体   >   FOXP2 antibody - N-terminal region   

FOXP2 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • 2 - FOXP2 antibody - N-terminal region AI10103
    FOXP2 antibody - N-terminal region (AI10103) in Human Kidney cells using Immunohistochemistry
    Rabbit Anti-FOXP2 Antibody
    Paraffin Embedded Tissue: Human Kidney
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 µg/ml
    Magnification: 400X
  • 1 - FOXP2 antibody - N-terminal region AI10103
    FOXP2 antibody - N-terminal region (AI10103) in Human HepG2 cells using Western Blot
    WB Suggested Antibody Titration: 0.2-1 µg/ml
    Positive Control: HepG2
  • 1 - FOXP2 antibody - N-terminal region AI10103
    FOXP2 antibody - N-terminal region (AI10103) in Human HepG2 cells using Western Blot
    WB Suggested Anti-FOXP2 Antibody Titration: 0.5 µg/ml
    Positive Control: HepG2 cell lysate
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession O15409
Other Accession O15409-5, NP_055306, NM_014491
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Dog, Horse
Predicted Human, Mouse, Rat, Pig, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 79919 Da
Additional Information
Gene ID 93986
Alias Symbol SPCH1, CAGH44, TNRC10
Other Names Forkhead box protein P2, CAG repeat protein 44, Trinucleotide repeat-containing gene 10 protein, FOXP2, CAGH44, TNRC10
Target/Specificity FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-FOXP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFOXP2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXP2
Synonyms CAGH44, TNRC10
Function Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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