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Pcbd1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P61458 |
| Other Accession | NM_025273, NP_079549 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Dog, Bovine, Yeast |
| Predicted | Human, Zebrafish, Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 11986 Da |
| Gene ID | 13180 |
|---|---|
| Alias Symbol | Dcoh, Pcbd |
| Other Names | Pterin-4-alpha-carbinolamine dehydratase, PHS, 4.2.1.96, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD, Pcbd1, Dcoh, Pcbd |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Pcbd1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Pcbd1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pcbd1 |
|---|---|
| Synonyms | Dcoh, Pcbd |
| Function | Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity). Also acts as a coactivator for HNF1B-dependent transcription (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P61459}. Nucleus {ECO:0000250|UniProtKB:P61459}. Note=Recruited to the nucleus through the interaction with HNF1B. {ECO:0000250|UniProtKB:P35680} |
| Tissue Location | Mainly expressed in the liver, in pancreatic cells, and in the kidney, especially in the distal convoluted tubule, in the cortical thick ascending limb of Henle's loop and in the connecting tubule. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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