癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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Ccnl1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9R1Q2 |
| Other Accession | NM_053662, NP_446114 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Dog, Bovine |
| Predicted | Human, Mouse, Rat, Zebrafish, Chicken, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59791 Da |
| Gene ID | 114121 |
|---|---|
| Alias Symbol | Ania-6a, Ccnl|MGC93069, Ccnl |
| Other Names | Cyclin-L1, Cyclin-L, Cyclin Ania-6a, Ccnl1, Ania6a |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Ccnl1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Ccnl1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Ccnl1 |
|---|---|
| Synonyms | Ania6a |
| Function | Involved in pre-mRNA splicing (PubMed:11683997). Functions in association with cyclin-dependent kinases (CDKs). May play a role in the regulation of RNA polymerase II (pol II). Inhibited by the CDK- specific inhibitor CDKN1A/p21 (By similarity). |
| Cellular Location | Nucleus speckle. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9UK58}. Note=Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing |
| Tissue Location | Ubiquitous with higher level in liver; expressed in striatal neurons. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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