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KCNH3 antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9ULD8 |
| Other Accession | NM_012284, NP_036416 |
| Reactivity | Human, Mouse, Rat, Rabbit, Dog, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 117129 Da |
| Gene ID | 23416 |
|---|---|
| Alias Symbol | BEC1, ELK2, KIAA1282, Kv12.2 |
| Other Names | Potassium voltage-gated channel subfamily H member 3, Brain-specific eag-like channel 1, BEC1, Ether-a-go-go-like potassium channel 2, ELK channel 2, ELK2, Voltage-gated potassium channel subunit Kv12.2, KCNH3, KIAA1282 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-KCNH3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | KCNH3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KCNH3 (HGNC:6252) |
|---|---|
| Synonyms | KIAA1282 |
| Function | Pore-forming (alpha) subunit of a voltage-gated inwardly rectifying potassium channel (PubMed:10455180). Charactherized by a fast rate of activation during depolarization followed by a rapid inactivation at much more depolarized value causing inward rectification due to a C-type inactivation mechanism (PubMed:10455180). Exhibits a rapid recovery from inactivation (PubMed:10455180). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9WVJ0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9WVJ0} Note=Expression on the cell membrane requires at least one of the three glycosylation sites to carry a sugar chain irrespective of their positions. {ECO:0000250|UniProtKB:Q9WVJ0} |
| Tissue Location | Detected only in brain, in particular in the telencephalon (PubMed:10455180). Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus (PubMed:10455180) |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Gutman,G.A., (2005) Pharmacol. Rev. 57 (4), 473-508 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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