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GNAS antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q5FWY2 |
| Other Accession | NM_080426, NP_536351 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Dog, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44250 Da |
| Gene ID | 2778 |
|---|---|
| Alias Symbol | AHO, C20orf45, GNAS1, GNASXL, GPSA, GSA, GSP, NESP, NESP55, PHP1A, PHP1B, POH, XL2, XLalphas, PHP1C |
| Other Names | GNAS complex locus , GNAS |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-GNAS antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GNAS antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GNAS {ECO:0000313|EMBL:AAH89157.2} |
|---|---|
| Function | Guanine nucleotide-binding protein (G protein) involved as transducer in olfactory signal transduction controlled by G protein- coupled receptors (GPCRs). Contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP- bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. GNAL/G(olf) alpha specifically mediates olfactory signal transduction within the olfactory neuroepithelium and the basal ganglia following GPCRs activation. Acts by promoting the specific activation of adenylyl cyclase ADCY3, resulting in increased levels of the signaling molecule cAMP. |
| Cellular Location | Cell membrane {ECO:0000256|ARBA:ARBA00004193}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004193} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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