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Slc25a27 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9D6D0 |
| Other Accession | NM_028711, NP_082987 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine, Sheep |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35798 Da |
| Gene ID | 74011 |
|---|---|
| Alias Symbol | 3632410G24Rik, 9430092A03Rik, D530043E16Rik, Ucp4 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Slc25a27 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Slc25a27 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Slc25a27 {ECO:0000312|MGI:MGI:1921261} |
|---|---|
| Function | Facilitates proton transport across the inner mitochondrial membrane and may dissipate excessive proton gradient associated with oxidative and metabolic stress at neuronal synapses. Regulates glutamate-induced proton conductance in astrocytes, shifting the energy metabolism toward aerobic glycolysis and lactate transfer to neurons for ATP synthesis. Can transport chloride ions with lower efficiency. The transport mechanism remains to be elucidated. |
| Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, neuron projection. Note=Localizes to neuronal cell body and processes. Within mitochondrial inner membrane, it is mainly observed in the inner boundary membrane locally separated from F(1)F(0) ATP synthase, which is preferentially localized in cristae |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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