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KIAA1754L antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q6GPH6 |
| Other Accession | NM_001008949, NP_001008949 |
| Reactivity | Human, Rat, Dog, Bovine |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 63395 Da |
| Gene ID | 150771 |
|---|---|
| Alias Symbol | KIAA1754L |
| Other Names | Inositol 1, 4, 5-trisphosphate receptor-interacting protein-like 1, ITPRIPL1, KIAA1754L |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-KIAA1754L antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | KIAA1754L antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ITPRIPL1 (HGNC:29371) |
|---|---|
| Synonyms | KIAA1754L |
| Function | Functions as a ligand of CD3E, inhibiting TCR-CD3 complex signaling to regulate T cell activation. Induces stable CD3E-NCK1 binding, thereby preventing the CD3E-ZAP70 interaction and subsequently inhibiting the activation of the downstream ERK-NFkB signaling cascade and calcium influx. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in testis and tumoral cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Brandenberger,R.,(2004)Nat.Biotechnol.22(6),707-716ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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