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Mafk antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q61827 |
| Other Accession | NM_010757, NP_034887 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Dog, Guinea Pig, Bovine |
| Predicted | Human, Mouse, Rat, Chicken, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 17537 Da |
| Gene ID | 17135 |
|---|---|
| Alias Symbol | AW061068, NF-E2, Nfe2u |
| Other Names | Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit, Mafk, Nfe2u |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Mafk antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Mafk antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Mafk |
|---|---|
| Synonyms | Nfe2u |
| Function | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (By similarity). However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites (PubMed:9240432). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Highly expressed in heart, skeletal muscle and placenta. Also expressed in erythroid cells |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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