癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
E130311K13Rik antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8BN57 |
| Other Accession | XM_002725647, XP_002725693 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33668 Da |
| Gene ID | 329659 |
|---|---|
| Other Names | Protein C3orf33 homolog, CC033 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-E130311K13Rik antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | E130311K13Rik antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Miso1 {ECO:0000250|UniProtKB:Q6P1S2} |
|---|---|
| Function | Regulates mitochondrial morphology and mitochondrial DNA (mtDNA) homeostasis (PubMed:41398051). Promotes the formation of specialized mitochondrial subdomains called small MTFP1-enriched mitochondria (SMEM) (By similarity). Negatively regulates mitochondrial fusion by excluding fusion coordinator OPA1 from SMEM (By similarity). Recruits mtDNA, potentially through interaction with SSBP1, and facilitates mtDNA transport to the mitochondrial periphery (By similarity). Also recruits other proteins, including PHB1, PHB2 and MTFP1, into SMEM which promotes peripheral mitochondrial fission, facilitating lysosome-mediated clearance of damaged mtDNA via mitophagy (By similarity). |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein. Note=Assembles into discrete subdomains known as small MTFP1-enriched mitochondria (SMEM). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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