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LOC640502 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q91YN5 |
| Other Accession | http://www.ncbi.nlm.nih.gov/nuccore/XM_917484, http://www.ncbi.nlm.nih.gov/protein/68566143?report=genbank&log$=protalign&blast_rank=15&RID=C8TKD8AJ016 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 58609 Da |
| Gene ID | 107652 |
|---|---|
| Alias Symbol | AgX, AGX1, AGX-1, AGX-2, SPAG2, ESTM38, AA420407, AA437972 |
| Other Names | UDP-N-acetylhexosamine pyrophosphorylase, UDP-N-acetylgalactosamine pyrophosphorylase, 2.7.7.83, UDP-N-acetylglucosamine pyrophosphorylase, 2.7.7.23, Uap1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LOC640502 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LOC640502 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Uap1 {ECO:0000312|MGI:MGI:1334459} |
|---|---|
| Function | Catalyzes the last step in biosynthesis of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) by converting UTP and glucosamine 1-phosphate (GlcNAc-1-P) to the sugar nucleotide (By similarity). Also converts UTP and galactosamine 1-phosphate (GalNAc-1- P) into uridine diphosphate-N-acetylgalactosamine (UDP-GalNAc) (By similarity). In addition to its role in metabolism, acts as a regulator of innate immunity in response to virus infection (PubMed:36603579). Regulates innate immunity by catalyzing pyrophosphorylation of IRF3 phosphorylated at 'Ser-386' by TBK1, promoting IRF3 dimerization and activation, leading to type I interferon responses (By similarity). |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q16222} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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