癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
B3gnt7 antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8K0J2 |
| Other Accession | NM_145222, NP_660257 |
| Reactivity | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse |
| Predicted | Rabbit, Pig, Dog, Guinea Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45379 Da |
| Gene ID | 227327 |
|---|---|
| Alias Symbol | C330001H22Rik, beta-3GnT7 |
| Other Names | UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7, BGnT-7, Beta-1, 3-Gn-T7, Beta-1, 3-N-acetylglucosaminyltransferase 7, Beta3Gn-T7, 2.4.1.-, B3gnt7 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-B3gnt7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | B3gnt7 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | B3gnt7 |
|---|---|
| Function | N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non- reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6- sulfoGlcNAcbeta)1->] within keratan sulfate polymer (By similarity). Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (PubMed:29625490). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (PubMed:12061784). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Strongly expressed in placenta and colon. Moderately expressed in lung, stomach, small intestine and kidney. Very weakly expressed in cerebrum, cerebellum, heart and testis |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Kataoka K.,et al.Biochem. Biophys. Res. Commun. 294:843-848(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
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