Galnt11 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | Q921L8 |
| Other Accession | NM_199393, NP_955425 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rabbit, Pig, Chicken, Dog, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 69201 Da |
| Gene ID | 231050 |
|---|---|
| Alias Symbol | Galnt11 |
| Other Names | Polypeptide N-acetylgalactosaminyltransferase 11, 2.4.1.41, Polypeptide GalNAc transferase 11, GalNAc-T11, pp-GaNTase 11, Protein-UDP acetylgalactosaminyltransferase 11, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11, Galnt11 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Galnt11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Galnt11 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Galnt11 |
|---|---|
| Function | Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O- glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO) (By similarity). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Mainly expressed in kidney. Weakly expressed in other tissues. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Schwientek T.,et al.J. Biol. Chem. 277:22623-22638(2002).
Shimoji S.,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Boskovski M.T.,et al.Nature 504:456-459(2013).
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