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为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GNPTAB antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q3T906 |
| Other Accession | NM_024312, NP_077288 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Zebrafish, Chicken, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 143622 Da |
| Gene ID | 79158 |
|---|---|
| Alias Symbol | DKFZp762B226, GNPTA, ICD, KIAA1208, MGC4170 |
| Other Names | N-acetylglucosamine-1-phosphotransferase subunits alpha/beta, 2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta, N-acetylglucosamine-1-phosphotransferase subunit alpha, N-acetylglucosamine-1-phosphotransferase subunit beta, GNPTAB, GNPTA, KIAA1208 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GNPTAB antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GNPTAB antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GNPTAB |
|---|---|
| Synonyms | GNPTA, KIAA1208 |
| Function | Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment. |
| Cellular Location | [N-acetylglucosamine-1-phosphotransferase subunit alpha]: Golgi apparatus membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Tiede S.,et al.Nat. Med. 11:1109-1112(2005).
Kudo M.,et al.J. Biol. Chem. 280:36141-36149(2005).
Kudo M.,et al.J. Biol. Chem. 280:42476-42476(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nagase T.,et al.DNA Res. 6:337-345(1999).
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