注册 | 登录
点击这里给我发消息
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   癌症   >   STEAP4 antibody - C-terminal region   

STEAP4 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - STEAP4 antibody - C-terminal region AI13090

    WB Suggested Anti-STEAP4 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Jurkat cell lysate
  • 产品详情
  • 实验流程
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q687X5
Other Accession NM_024636, NP_078912
Reactivity Human, Rabbit, Bovine
Predicted Rabbit
Host Rabbit
Clonality Polyclonal
Calculated MW 51981 Da
Additional Information
Gene ID 79689
Alias Symbol DKFZp666D049, FLJ23153, STAMP2, TIARP, TNFAIP9
Other Names Metalloreductase STEAP4, 1.16.1.-, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor, alpha-induced protein 9, STEAP4, STAMP2, TNFAIP9
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-STEAP4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSTEAP4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STEAP4
Synonyms STAMP2 {ECO:0000303|PubMed:15897894}, TN
Function Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (PubMed:30337524). Can also reduce Cu(2+) to Cu(1+) (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance (PubMed:18381574, PubMed:18430367). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage- independent cell proliferation (PubMed:19787193).
Cellular Location Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein
Tissue Location Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Korkmaz C.G.,et al.Oncogene 24:4934-4945(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ohgami R.S.,et al.Nat. Genet. 37:1264-1269(2005).
Zhang C.M.,et al.Acta Pharmacol. Sin. 29:587-592(2008).

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价