癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
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CAND2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O75155 |
| Other Accession | NM_012298, NP_036430 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 135256 Da |
| Gene ID | 23066 |
|---|---|
| Alias Symbol | KIAA0667, TIP120B, Tp120b |
| Other Names | Cullin-associated NEDD8-dissociated protein 2, Cullin-associated and neddylation-dissociated protein 2, Epididymis tissue protein Li 169, TBP-interacting protein of 120 kDa B, TBP-interacting protein 120B, p120 CAND2, CAND2, KIAA0667, TIP120B |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CAND2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CAND2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CAND2 |
|---|---|
| Synonyms | KIAA0667, TIP120B |
| Function | Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in epididymis (at protein level). |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Bienvenut W.V.,et al.Submitted (MAR-2009) to UniProtKB.
Bienvenut W.V.,et al.Submitted (MAR-2009) to UniProtKB.
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
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