癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PLG antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q5R8X6 |
| Other Accession | NM_000301, NP_000292 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog |
| Predicted | Human, Mouse, Pig, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 90380 Da |
| Gene ID | 100172984 |
|---|---|
| Alias Symbol | DKFZp779M0222 |
| Other Names | Plasminogen, 3.4.21.7, Plasmin heavy chain A, Activation peptide, Plasmin heavy chain A, short form, Plasmin light chain B, PLG |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PLG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PLG antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PLG {ECO:0000250|UniProtKB:P00747} |
|---|---|
| Function | [Plasmin]: Protease which primary function is to degrade fibrin, the main component of blood clots. Also cleaves other components of blood clots like thrombospondin-1/THBS1 and von Willebrand factor/VWF. Can also directly and/or through the activation of other proteases degrade the various components of the extracellular matrix including collagen, fibronectin and laminin. Thereby, regulates a variety of biological processes including embryonic development, tissue remodeling, and inflammation (By similarity). In ovulation, weakens the walls of the Graafian follicle (By similarity). In vitro, it is also able to cleave several complement zymogens, such as C1, C4 and C5 (By similarity). |
| Cellular Location | [Plasmin]: Secreted {ECO:0000250|UniProtKB:P00747}. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin Interaction with HRG tethers it to the cell surface {ECO:0000250|UniProtKB:P00747} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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