癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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SHCBP1L antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9BZQ2 |
| Other Accession | NM_030933, NP_112195 |
| Reactivity | Human |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 72632 Da |
| Gene ID | 81626 |
|---|---|
| Alias Symbol | GE36, MGC26911, MGC48296, SHCBP1L, C1orf14 |
| Other Names | SHC SH2 domain-binding protein 1-like protein, SHCBP1L, C1orf14 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SHCBP1L antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SHCBP1L antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SHCBP1L (HGNC:16788) |
|---|---|
| Synonyms | C1orf14 |
| Function | Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells. |
| Cellular Location | Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q3TTP0}. Note=Colocalizes with alpha tubulin during meiosis. Colocalizes with HSPA2 at spindle during the meiosis process. {ECO:0000250|UniProtKB:Q3TTP0} |
| Tissue Location | Expressed in spermatocytes and elongating spermatids inside the seminiferous tubules (at protein level) (PubMed:24557841). Testis-specific (PubMed:11318611, PubMed:24557841) |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Sood R.,et al.Genomics 73:211-222(2001).
Gregory S.G.,et al.Nature 441:315-321(2006).
Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
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