癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LOC681989 Antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q5PQN6 |
| Other Accession | NM_001101004, NP_001094474 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53305 Da |
| Gene ID | 681989 |
|---|---|
| Alias Symbol | Spe39, Vipar, hSPE-39 |
| Other Names | Spermatogenesis-defective protein 39 homolog, hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction, Vipas39, Spe39, Vipar |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LOC681989 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LOC681989 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Vipas39 |
|---|---|
| Synonyms | Spe39, Vipar |
| Function | Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B. May play a role in vesicular trafficking during spermatogenesis. May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity). |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle. Early endosome {ECO:0000250|UniProtKB:Q9H9C1}. Recycling endosome {ECO:0000250|UniProtKB:Q9H9C1}. Late endosome {ECO:0000250|UniProtKB:Q9H9C1}. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles. {ECO:0000250|UniProtKB:Q9H9C1} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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