癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TAAR5 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB, IF |
|---|---|
| Primary Accession | O14804 |
| Other Accession | NM_003967, NP_003958 |
| Reactivity | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38242 Da |
| Gene ID | 9038 |
|---|---|
| Alias Symbol | MGC138414, MGC138416, PNR, RP11-295F4.5 |
| Other Names | Trace amine-associated receptor 5, TaR-5, Trace amine receptor 5, hTaar5, Putative neurotransmitter receptor, TAAR5, PNR |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TAAR5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TAAR5 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TAAR5 {ECO:0000303|PubMed:15718104, ECO:0000312|HGNC:HGNC:30236} |
|---|---|
| Function | Olfactory receptor specific for trimethylamine, a trace amine (PubMed:23393561). Also activated at lower level by dimethylethylamine (PubMed:23393561). Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food (PubMed:23393561). Trimethylamine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (PubMed:23393561). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus (PubMed:9464258). Weak expression is also find in substantia nigra (PubMed:9464258) |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Zeng Z.,et al.Biochem. Biophys. Res. Commun. 242:575-578(1998).
Lindemann L.,et al.Genomics 85:372-385(2005).
Staubert C.,et al.PLoS ONE 5:E11133-E11133(2010).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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