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>   首页   >   产品   >   一抗   >   神经科学   >   OPN1MW antibody - C-terminal region   

OPN1MW antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - OPN1MW antibody - C-terminal region AI14458

    WB Suggested Anti-OPN1MW Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: HepG2 cell lysate
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P04000
Other Accession NM_000513, NP_000504
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rabbit
Host Rabbit
Clonality Polyclonal
Calculated MW 40574 Da
Additional Information
Gene ID 5956
Alias Symbol CBBM, CBD, GCP, MGC176615, MGC177321, MGC198468, MGC198469, OPN1MW1, OPN1MW2, GOP, COD5
Other Names Long-wave-sensitive opsin 1, Red cone photoreceptor pigment, Red-sensitive opsin, ROP, OPN1LW, RCP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OPN1MW antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOPN1MW antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name OPN1LW (HGNC:9936)
Synonyms RCP
Function G protein-coupled photoreceptor that selectively activates G(i) proteins in response to long-wavelength (red) light, thereby decreasing intracellular cAMP levels (PubMed:2937147, PubMed:6140680, Ref.5). Activation occurs when the opsin-bound cis-retinal chromophore absorbs a photon and isomerizes to all-trans-retinal, inducing a conformational change in the opsin that triggers a G protein-mediated phototransduction cascade (Ref.5). Mediates visual perception of red light in cone photoreceptor cells (PubMed:12051694, PubMed:8213841, PubMed:8666378).
Cellular Location Membrane; Multi-pass membrane protein. Photoreceptor outer segment membrane; Multi-pass membrane protein
Tissue Location The red (OPN1LW), green (OPN1MW), and blue (OPN1SW) photoreceptor pigments are found in cone cells
Research Areas

REFERENCES

Nathans J.,et al.Science 232:193-202(1986).
Ross M.T.,et al.Nature 434:325-337(2005).
Applebury M.L.,et al.Vision Res. 26:1881-1895(1986).
Winderickx J.,et al.Nature 356:431-433(1992).
Nathans J.,et al.Am. J. Hum. Genet. 53:987-1000(1993).

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