OPN1MW antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | P04000 |
| Other Accession | NM_000513, NP_000504 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 40574 Da |
| Gene ID | 5956 |
|---|---|
| Alias Symbol | CBBM, CBD, GCP, MGC176615, MGC177321, MGC198468, MGC198469, OPN1MW1, OPN1MW2, GOP, COD5 |
| Other Names | Long-wave-sensitive opsin 1, Red cone photoreceptor pigment, Red-sensitive opsin, ROP, OPN1LW, RCP |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-OPN1MW antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | OPN1MW antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | OPN1LW (HGNC:9936) |
|---|---|
| Synonyms | RCP |
| Function | G protein-coupled photoreceptor that selectively activates G(i) proteins in response to long-wavelength (red) light, thereby decreasing intracellular cAMP levels (PubMed:2937147, PubMed:6140680, Ref.5). Activation occurs when the opsin-bound cis-retinal chromophore absorbs a photon and isomerizes to all-trans-retinal, inducing a conformational change in the opsin that triggers a G protein-mediated phototransduction cascade (Ref.5). Mediates visual perception of red light in cone photoreceptor cells (PubMed:12051694, PubMed:8213841, PubMed:8666378). |
| Cellular Location | Membrane; Multi-pass membrane protein. Photoreceptor outer segment membrane; Multi-pass membrane protein |
| Tissue Location | The red (OPN1LW), green (OPN1MW), and blue (OPN1SW) photoreceptor pigments are found in cone cells |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Nathans J.,et al.Science 232:193-202(1986).
Ross M.T.,et al.Nature 434:325-337(2005).
Applebury M.L.,et al.Vision Res. 26:1881-1895(1986).
Winderickx J.,et al.Nature 356:431-433(1992).
Nathans J.,et al.Am. J. Hum. Genet. 53:987-1000(1993).
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