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STOM antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 3 - STOM antibody - C-terminal region AI14668
    Sample Type : HeLa cells
    Primary Antibody Dilution : 1:150
    Secondary Antibody : Goat anti-rabbit-Alexa Fluor 488 Secondary Antibody Dilution : 1:800 Color/Signal Descriptions : Green: STOMBlue: DAPI
    Gene Name : STOM Submitted by : COCOLA Cinzia, Stem Cell Biology and Cancer Research Unit
  • 1 - STOM antibody - C-terminal region AI14668

    WB Suggested Anti-STOM Antibody Titration: 1.0 μg/ml
    Positive Control: Hela Whole CellSTOM is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF
Primary Accession P27105
Other Accession NM_004099, NP_004090
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Dog, Guinea Pig, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 31731 Da
Additional Information
Gene ID 2040
Alias Symbol BND7, EPB7, EPB72
Other Names Erythrocyte band 7 integral membrane protein, Protein 7.2b, Stomatin, STOM, BND7, EPB72
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-STOM antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSTOM antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STOM (HGNC:3383)
Function Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190) Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545).
Tissue Location Detected in erythrocytes (at protein level). Widely expressed.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Hiebl-Dirschmied C.M.,et al.Biochim. Biophys. Acta 1090:123-124(1991).
Stewart G.W.,et al.Blood 79:1593-1601(1992).
Unfried I.,et al.Genomics 30:521-528(1995).
Gallagher P.G.,et al.J. Biol. Chem. 270:26358-26363(1995).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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