Angpt2 Antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
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Primary Accession | O35608 |
Other Accession | NM_007426, NP_031452 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine, Sheep |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine, Sheep |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56576 Da |
Gene ID | 11601 |
---|---|
Alias Symbol | Agpt2, Ang-2, Ang2 |
Other Names | Angiopoietin-2, ANG-2, Angpt2, Agpt2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Angpt2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Angpt2 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Angpt2 |
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Synonyms | Agpt2 |
Function | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (By similarity). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (By similarity). In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression (By similarity). In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). Involved in the regulation of lymphangiogenesis (PubMed:28179430, PubMed:32908006). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:O15123}. |
Tissue Location | Expressed in the ovary, uterus and placenta. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Maisonpierre P.C.,et al.Science 277:55-60(1997).
Carninci P.,et al.Science 309:1559-1563(2005).

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