NRTN antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
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Primary Accession | Q99748 |
Other Accession | NM_004558, NP_004549 |
Reactivity | Human, Mouse, Rat, Pig, Dog, Guinea Pig, Bovine |
Predicted | Human, Mouse, Rat, Pig, Chicken, Guinea Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22405 Da |
Gene ID | 4902 |
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Alias Symbol | NTN |
Other Names | Neurturin, NRTN |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-NRTN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | NRTN antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NRTN {ECO:0000303|PubMed:31535977, ECO:0000312|HGNC:HGNC:8007} |
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Function | Growth factor that supports the survival of sympathetic neurons in culture (PubMed:8945474). May regulate the development and maintenance of the CNS (PubMed:8945474). Involved in the development of the neural crest (PubMed:15242795). Might control the size of non- neuronal cell population such as haemopoietic cells (PubMed:8945474). Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor (PubMed:10829012, PubMed:29414779, PubMed:31535977). Heparan sulfate- binding is required for signaling (PubMed:29414779). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:P97463}. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.

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