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>   首页   >   产品   >   一抗   >   神经科学   >   NRTN antibody - C-terminal region   

NRTN antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - NRTN antibody - C-terminal region AI14997

    WB Suggested Anti-NRTN Antibody Titration: 1.0 μg/ml
    Positive Control: THP-1 Whole Cell

WB Suggested Anti-NRTN Antibody Titration: 1.0 μg/ml
Positive Control: THP-1 Whole Cell
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99748
Other Accession NM_004558, NP_004549
Reactivity Human, Mouse, Rat, Pig, Dog, Guinea Pig, Bovine
Predicted Human, Mouse, Rat, Pig, Chicken, Guinea Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 22405 Da
Additional Information
Gene ID 4902
Alias Symbol NTN
Other Names Neurturin, NRTN
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-NRTN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNRTN antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRTN {ECO:0000303|PubMed:31535977, ECO:0000312|HGNC:HGNC:8007}
Function Growth factor that supports the survival of sympathetic neurons in culture (PubMed:8945474). May regulate the development and maintenance of the CNS (PubMed:8945474). Involved in the development of the neural crest (PubMed:15242795). Might control the size of non- neuronal cell population such as haemopoietic cells (PubMed:8945474). Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor (PubMed:10829012, PubMed:29414779, PubMed:31535977). Heparan sulfate- binding is required for signaling (PubMed:29414779).
Cellular Location Secreted {ECO:0000250|UniProtKB:P97463}.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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